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Charleskag
02 Apr 2025 - 11:01 am
Aged 15, New Zealander Sam Ruthe has already run a four-minute mile. He would ‘love to try and qualify’ for the 2028 Olympics
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Sam Ruthe had the eyes of thousands on him when he stepped onto a running track in Auckland just over a week ago.
Undaunted by the occasion, Ruthe went on to become the first 15-year-old to run a sub-four-minute mile, even managing a nonchalant shrug of the shoulders as he crossed the finish line.
The race was almost entirely engineered for the high school student to break the fabled four-minute barrier – a feat first achieved by Roger Bannister more than 70 years ago – but the weight of running history was a burden that Ruthe seemed to bear lightly.
The first three laps, he later said in a video documenting the race, “felt pretty comfortable – nothing too crazy.”
Perhaps the most intimidating part of his achievement occurred when Ruthe returned to school the next day, only to be immediately called into the principal’s office.
“He’s like, ‘Alright, so you’re gonna have to go up on stage and we’ll get the whole school to clap you,’” Ruthe tells CNN Sports’ Patrick Snell. “It was really scary, actually. I headed into class and everyone thought I was famous.”
It’s easy to forget, given his history-making performance last week, that Ruthe is like most other 15-year-olds in New Zealand. He goes to school, spends time with his friends, and helps with chores around the house.
He also just happens to be one of the most exciting middle-distance runners on the planet, one of the latest star athletes to emerge from sports-mad New Zealand.
Peternet
02 Apr 2025 - 06:50 am
Exposure to phthalates during pregnancy can affect a newborn’s brain development, study finds
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Phthalates — the synthetic chemicals used in everyday products for food packaging, personal care, toys and more — have been linked to abnormal neurological development in infants.
Now, scientists may have discovered a biological pathway for how this phenomenon could occur. Researchers found that in utero exposure to phthalates is linked with altered metabolism of neurotransmitters and amino acids involved in brain maturation, according to a study published Wednesday in the journal Nature Communications.
The report is the first to use untargeted metabolomics — the study of all small molecules or metabolites in a biological system — to connect a mother’s phthalate exposure to a newborn’s metabolites, and those metabolites to neurological development, said senior study author Dr. Donghai Liang via email.
“This represents an important step forward in understanding how prenatal chemical exposures shape infant development at the molecular level,” added Liang, an associate professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta.
First introduced in the 1920s, phthalates are used to make plastics softer and more flexible, primarily in polyvinyl chloride (PVC) products such as vinyl flooring, medical devices, children’s toys, food packaging or shower curtains. The chemicals also help lubricate substances and carry fragrances in various personal care products including deodorant; nail polish; perfumes; hair gels, sprays or shampoos; soaps; and body lotions.
Phthalates are also endocrine disruptors that have been linked to preterm birth, infant genital abnormalities, childhood obesity, asthma, cancer, cardiovascular issues, and low sperm count and testosterone in men.
“We conducted this study because phthalates are everywhere in our daily lives,” Liang said, hence their nickname “everywhere chemicals.”
Harming infant health
The findings are based on mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort between 2016 and 2018. In urine samples collected from 216 mothers between eight weeks and 14 weeks of gestation at visit one and 145 participants between 24 and 30 weeks’ gestation at visit two, the authors measured eight phthalate metabolites. Participants were around age 24 on average, and their levels of some phthalate metabolites were higher than the average determined by the National Health and Nutrition Examination Survey.
Within a day or two of birth, the authors collected the babies’ blood via a heel stick.
The team found prenatal phthalate levels were associated with lower levels of tyrosine, an amino acid and precursor to the thyroid hormone thyroxine. Thyroxine was also abnormally low in those with in utero phthalate exposure, and low thyroxine has been previously associated with greater vulnerability to illness and neurodevelopmental issues in newborns, the authors said. Tyrosine is also a precursor to the neurotransmitters dopamine, norepinephrine and epinephrine, all of which partly contribute to the body’s fight-or-flight response. Low levels of these neurotransmitters can lead to various problems, including anxiety, depression and trouble focusing.
Prenatal phthalate exposure was also linked with lower levels of the essential amino acid tryptophan, which converts into 5-hydroxytryptophan (or 5-HTP), which then turns into serotonin. Both 5-HTP and serotonin were also low. Serotonin has several critical roles in the body, including mood regulation, sleep, learning, memory, digestion and the body’s response to stress. Previous research has linked low serotonin with mood disorders such as depression and anxiety, sleep problems, and digestive issues.
Terryhem
02 Apr 2025 - 04:52 am
The voice of ‘White Lotus’ star Walton Goggins is the lullaby we didn’t know we needed
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While his “White Lotus” character Rick has been the source of some stress this season, Walton Goggins is here to soothe us into a state of dreamy sleep to make up for it.
The actor has partnered with relaxation and meditation app Calm for one of their famed Sleep Stories, lending his smoky voice to a fable titled “The Yard Sale.”
Goggins announced the Sleep Story on his verified Instagram on Tuesday, writing, “A friend once said to me the first question you ask someone shouldn’t be, ‘How are you?’ but rather, ‘How did you sleep last night?’ I agree.”
The post included an excerpt from the story, in which Goggins is heard languidly instructing listeners to relax their bodies and get into bed. “You could even climb into a hammock,” he added. “I wouldn’t do that because I’ve never gracefully got in or out of one.”
In the caption, the actor also wrote that he “wanted to create a Sleep Story that feels dreamlike, helping people slow their minds down by wandering through a yard sale (which happens to be one of my favorite things to do), uncovering hidden treasures.”
“It’s the Walton Goggins version of counting sheep. I hope you enjoy,” he added.
Other celebrities who have read bedtime stories in the hopes of putting audiences to sleep include Dolly Parton and the late Jimmy Stewart, whose voice was featured in a Calm Christmas Sleep Story in 2023 thanks to generative AI technology.
Goggins currently stars on “The White Lotus,” where his character is often the most stressed out and tortured of the ensemble, at one point setting a slew of snakes free.
Robertknine
02 Apr 2025 - 04:37 am
Look of the Week: Naomi Watts is twinning with her canine co-star
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What’s white and black and red all over? Naomi Watts and her 145lb co-star, Bing, a Great Dane, taking a dog walk on the crimson carpet for the New York premiere of “The Friend.”
Directed by Scott Mcgehee and adapted from Sigrid Nunez’s 2018 novel of the same name, the film — set to release in US theaters on March 28 and in the UK on April 25 — follows a solitary writer and teacher named Iris whose life is upended after a close friend bequeaths his giant pet dog to her following his death.
In front of the cameras Monday evening, the “Mulholland Drive” actor and Bing looked like they were cut from the same cloth — both in temperament and in their matching black polka dots. Watts was dressed in a white gown with fur-tufted spots that bore a striking resemblance to Bing’s own coat, but the Cruella de Vil comparisons ended there. Instead, Watts and Bing were captured in the throes of lots of paw-shakes, puppy kisses and head scratches.
The dress that Watts wore, titled the “Domino” and designed by Jacquemus, debuted during the Spring-Summer 2025 Paris couture shows in January. The look was both elegant and offbeat, with a high-cowl neck and open-back, asymmetrical waistline that mimicked a French tuck. It was styled with a skirt that sprouted furry black polka dots, which close up were unnervingly reminiscent of body hair. But from afar they gave the impression of soft-edged dabs of watercolor bleeding downstream.
The look was styled by Jeanann Williams, who has also been working with “The White Lotus” star Leslie Bibb. Williams’ decision to coordinate Watts with Bing was a new take on method dressing — the thematic styling trend that has dominated celebrity red carpets since Greta Gerwig’s “Barbie” in 2023. Since then, the sartorial trope, which connects actors to their on-screen characters through clothes, has become somewhat tired — with some observers claiming that the 7-month-long “Wicked” press tour, in which Cynthia Erivo and Ariana Grande became prisoners to the colors green and pink, was peak saturation.
Byrondig
02 Apr 2025 - 03:27 am
Critics say this power imbalance is clear in the 2016 contract Guyana signed with Exxon. Under the agreement, Exxon keeps 75% of everything it makes from its oil operations in Guyana, with the remaining 25% shared equally between the company and the government, which also takes a 2% royalty.
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“It was a bad deal,” Ali said in the BBC interview, but he has rejected the idea of unilaterally changing the agreement, which was signed by the previous government. He says the next contract with Exxon will be on different terms.
An Exxon spokesperson said the contract is “globally competitive for countries at a similar stage of exploration” and said Guyana is averaging $1 billion a year in “oil profits.”
Exxon has also faced a number of lawsuits over its potential environmental impact, many filed by Melinda Janki, a Guyanese international lawyer, who drafted the country’s Environmental Protection Act back in the 1990s.
A big victory for Guyana’s people and environment came in 2023, when the court ruled Exxon should have unlimited liability for the costs of any oil spill. Exxon has since appealed the ruling and has posted a $2 billion guarantee while it awaits the appeal outcome.
Exxon said this commitment supplements “its robust balance sheets … and the insurance policies they already had in place.” Janki says this isn’t enough. Offshore oil spills can be extremely expensive to deal with, the 2010 Deepwater Horizon spill cost nearly $70 billion to clean up.
The push and pull between those who say oil offers Guyana a brighter future and those who fear the industry’s impact will continue.
Exxon said it’s had a positive impact on the country, including employing more than 6,200 people, investing more than $2 billion with local Guyanese businesses since 2015 and spending more than $43 million on community projects.
Allaninsed
02 Apr 2025 - 01:22 am
A tiny rainforest country is growing into a petrostate. A US oil company could reap the biggest rewards
kyberswap
Guyana’s destiny changed in 2015. US fossil fuel giant Exxon discovered nearly 11 billion barrels of oil in the deep water off the coast of this tiny, rainforested country.
It was one of the most spectacular oil discoveries of recent decades. By 2019, Exxon and its partners, US oil company Hess and China-headquartered CNOOC, had started producing the fossil fuel.? They now pump around 650,000 barrels of oil a day, with plans to more than double this to 1.3 million by 2027.
Guyana now has the world’s highest expected oil production growth through 2035.
This country — sandwiched between Brazil, Venezuela and Suriname — has been hailed as a climate champion for the lush, well-preserved forests that carpet nearly 90% of its land. It is on the path to becoming a petrostate at the same time as the impacts of the fossil fuel-driven climate crisis escalate.
While the government says environmental protection and an oil industry can go hand-in-hand, and low-income countries must be allowed to exploit their own resources, critics say it’s a dangerous path in a warming world, and the benefits may ultimately skew toward Exxon — not Guyana.
Since Exxon’s transformative discovery, Guyana’s government has tightly embraced oil as a route to prosperity. In December 2019, then-President David Granger said in a speech, “petroleum resources will be utilized to provide the good life for all … Every Guyanese will benefit.”
It’s a narrative that has continued under current President Mohamed Irfaan Ali, who says new oil wealth will allow Guyana to develop better infrastructure, healthcare and climate adaptation.
Danielsmuff
01 Apr 2025 - 10:08 pm
‘White Lotus’ villain Jon Gries reveals the true crimes that inspired his twisty take on Greg/Gary
fixedfloat exchange
When Season 3 of “The White Lotus” premiered last month, the shock was palpable when returning character Belinda recognized a familiar face at the resort in Thailand: Greg Hunt, the wily suitor of the late Tanya McQuoid.
As the season has unfolded, Greg (played by Jon Gries) has emerged as an antagonist, particularly after Belinda dove into the investigation surrounding Tanya’s death and learned that Greg, who now goes by Gary, evaded questioning by authorities.
On a show famous for reinventing itself, the same has been asked of the actor, who says that playing the ever-shifting character has been a welcome challenge and, like “White Lotus” itself, full of twists.
“In the beginning, I totally played him for a guy who was, you know, on his last legs,” Gries said in a recent interview with CNN, referencing Greg’s very apparent ill health in the first season of “White Lotus,” which premiered to rave reviews in summer 2021. He added: “When you play a character, you want to find his empathetic side, and you want to understand where they came from, and what got them to where they are.”
But when he was contacted by creator Mike White about appearing in Season 2, Gries realized he would have to adjust his framing of Greg, despite having previously imagined a “comprehensive history” for him on his own.
“(White) said, ‘I’m writing it right now, and I’m writing you, and I just need to know here and now: If you’re in, I’ll continue writing. If not, I’ll stop,’” Gries recalled.
Herbertrag
01 Apr 2025 - 10:51 am
A tiny rainforest country is growing into a petrostate. A US oil company could reap the biggest rewards
swell network
Guyana’s destiny changed in 2015. US fossil fuel giant Exxon discovered nearly 11 billion barrels of oil in the deep water off the coast of this tiny, rainforested country.
It was one of the most spectacular oil discoveries of recent decades. By 2019, Exxon and its partners, US oil company Hess and China-headquartered CNOOC, had started producing the fossil fuel.? They now pump around 650,000 barrels of oil a day, with plans to more than double this to 1.3 million by 2027.
Guyana now has the world’s highest expected oil production growth through 2035.
This country — sandwiched between Brazil, Venezuela and Suriname — has been hailed as a climate champion for the lush, well-preserved forests that carpet nearly 90% of its land. It is on the path to becoming a petrostate at the same time as the impacts of the fossil fuel-driven climate crisis escalate.
While the government says environmental protection and an oil industry can go hand-in-hand, and low-income countries must be allowed to exploit their own resources, critics say it’s a dangerous path in a warming world, and the benefits may ultimately skew toward Exxon — not Guyana.
Billyhouse
01 Apr 2025 - 10:51 am
Mist and microlightning
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To recreate a scenario that may have produced Earth’s first organic molecules, researchers built upon experiments from 1953 when American chemists Stanley Miller and Harold Urey concocted a gas mixture mimicking the atmosphere of ancient Earth. Miller and Urey combined ammonia (NH3), methane (CH4), hydrogen (H2) and water, enclosed their “atmosphere” inside a glass sphere and jolted it with electricity, producing simple amino acids containing carbon and nitrogen. The Miller-Urey experiment, as it is now known, supported the scientific theory of abiogenesis: that life could emerge from nonliving molecules.
For the new study, scientists revisited the 1953 experiments but directed their attention toward electrical activity on a smaller scale, said senior study author Dr. Richard Zare, the Marguerite Blake Wilbur Professor of Natural Science and professor of chemistry at Stanford University in California. Zare and his colleagues looked at electricity exchange between charged water droplets measuring between 1 micron and 20 microns in diameter. (The width of a human hair is 100 microns.)
“The big droplets are positively charged. The little droplets are negatively charged,” Zare told CNN. “When droplets that have opposite charges are close together, electrons can jump from the negatively charged droplet to the positively charged droplet.”
The researchers mixed ammonia, carbon dioxide, methane and nitrogen in a glass bulb, then sprayed the gases with water mist, using a high-speed camera to capture faint flashes of microlightning in the vapor. When they examined the bulb’s contents, they found organic molecules with carbon-nitrogen bonds. These included the amino acid glycine and uracil, a nucleotide base in RNA.
“We discovered no new chemistry; we have actually reproduced all the chemistry that Miller and Urey did in 1953,” Zare said. Nor did the team discover new physics, he added — the experiments were based on known principles of electrostatics.
“What we have done, for the first time, is we have seen that little droplets, when they’re formed from water, actually emit light and get this spark,” Zare said. “That’s new. And that spark causes all types of chemical transformations.”
Carloswat
01 Apr 2025 - 09:59 am
Mindful wellness challenges
If you’re the type of person who thrives on challenges and pushing your limits, this doesn’t mean you need to shy away from wellness challenges altogether. But before diving in, take a step back and ask yourself if you’re pursuing the challenge for the right reasons, McGregor said.
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Some people want to try these challenges because they believe something is missing from their life, and they’re looking to attain “worth” or receive validation, McGregor noted.
A good way to assess your motivation is by considering whether the challenge will benefit your health or if it’s about showcasing your accomplishments on social media or some other reason.
Before trying any new trend, make sure you have the foundation to handle it and be aware of any potential risks, McGregor said.
For casual runners, this might mean signing up for a 5K but building your endurance gradually while incorporating other strength training exercises into your routine. For more intense challenges, such as a marathon, McGregor encourages people to consult with professionals or a coach who can monitor your progress and condition along the way.
Focusing on sustainable habits
Both McGregor and Curran emphasize the importance of fostering sustainable health habits before embarking on more extreme challenges.
Rather than chasing the idea of being “healthy,” McGregor suggests focusing on actual healthful behaviors and starting small.
If you’re a highly sedentary person and want to add more movement to your day, try doing lunges while brushing your teeth or taking short walks throughout your typical routine.